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Curcumin plays a synergistic role in combination with HSV-TK/GCV in inhibiting growth of murine B16 melanoma cells and melanoma xenografts

Melanoma is a global concern and accounts for the major mortality of skin cancers. Herpes simplex virus thymidine kinase gene with ganciclovir (HSV-TK/GCV) is a promising gene therapy for melanoma. Despite its low efficiency, it is well known for its bystander effect which is mainly mediated by gap...

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Detalles Bibliográficos
Autores principales: Li, Hong, Du, Haiyan, Zhang, Guangxian, Wu, Yingya, Qiu, Pengxiang, Liu, Jingjing, Guo, Jing, Liu, Xijuan, Sun, Lingling, Du, Biaoyan, Tan, Yuhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756137/
https://www.ncbi.nlm.nih.gov/pubmed/31579620
http://dx.doi.org/10.7717/peerj.7760