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PDGFR-induced autocrine SDF-1 signaling in cancer cells promotes metastasis in advanced skin carcinoma

Advanced and undifferentiated skin squamous cell carcinomas (SCCs) exhibit aggressive growth and enhanced metastasis capability, which is associated in mice with an expansion of the cancer stem-like cell (CSC) population and with changes in the regulatory mechanisms that control the proliferation an...

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Detalles Bibliográficos
Autores principales: Bernat-Peguera, Adrià, Simón-Extremera, Pilar, da Silva-Diz, Victoria, López de Munain, Mikel, Díaz-Gil, Laura, Penin, Rosa M., González-Suárez, Eva, Pérez Sidelnikova, Diana, Bermejo, Oriol, Viñals, Joan Maria, Viñals, Francesc, Muñoz, Purificación
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756210/
https://www.ncbi.nlm.nih.gov/pubmed/30874597
http://dx.doi.org/10.1038/s41388-019-0773-y