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Bone marrow MSCs in MDS: contribution towards dysfunctional hematopoiesis and potential targets for disease response to hypomethylating therapy

The study of myelodysplastic syndromes (MDS) in murine models has now indicated the possible involvement of the bone marrow microenvironment in the generation of dysplastic hematopoietic cells. However, there is scant work on patient samples and the role of hypomethylating agents on the bone marrow...

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Detalles Bibliográficos
Autores principales: Poon, Zhiyong, Dighe, Niraja, Venkatesan, Subhashree S., Cheung, Alice M. S., Fan, Xiubo, Bari, Sudipto, Hota, Monalisa, Ghosh, Sujoy, Hwang, William Y. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756222/
https://www.ncbi.nlm.nih.gov/pubmed/30575819
http://dx.doi.org/10.1038/s41375-018-0310-y