Exosomal Wnt-induced dedifferentiation of colorectal cancer cells contributes to chemotherapy resistance

Cancer stem cells (CSCs) are inherently resistant to chemotherapy, and CSCs in chemotherapy-failed recurrent tumors are enriched; however, the cellular origin of chemotherapy-induced CSC enrichment remains unclear. Communication with stromal fibroblasts may induce cancer cell dedifferentiation into...

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Detalles Bibliográficos
Autores principales: Hu, Y.-B., Yan, C., Mu, L., Mi, Y.–L., Zhao, H., Hu, H., Li, X.-L., Tao, D.-D., Wu, Y.-Q., Gong, J.-P., Qin, J.-C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756234/
https://www.ncbi.nlm.nih.gov/pubmed/30390075
http://dx.doi.org/10.1038/s41388-018-0557-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756234/
https://www.ncbi.nlm.nih.gov/pubmed/30390075
http://dx.doi.org/10.1038/s41388-018-0557-9

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