Loss of Stat6 affects chromatin condensation in intestinal epithelial cells causing diverse outcome in murine models of inflammation-associated and sporadic colon carcinogenesis

While great advances have been achieved regarding the genetic basis of colorectal cancer, the complex role of cell–cell communication and cytokine-induced signaling during its pathogenesis remains less understood. Signal transducer and activator of transcription 6 (Stat6) is the main transcription f...

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Detalles Bibliográficos
Autores principales: De Oliveira, Tiago, Ramakrishnan, Mallika, Diamanti, Michaela A., Ziegler, Paul K., Brombacher, Frank, Greten, Florian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756235/
https://www.ncbi.nlm.nih.gov/pubmed/30353167
http://dx.doi.org/10.1038/s41388-018-0551-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756235/
https://www.ncbi.nlm.nih.gov/pubmed/30353167
http://dx.doi.org/10.1038/s41388-018-0551-2

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