Ubiquitin ligase TRIM65 promotes colorectal cancer metastasis by targeting ARHGAP35 for protein degradation

Tripartite motif-containing protein 65 (TRIM65) is an E3 ubiquitin ligase and a critical regulator of a variety of cellular processes as well as tumor progression. Therefore, more substrates must be identified in the physiology or disease context. Here, we found that TRIM65 is upregulated and associ...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Daici, Li, Yichen, Zhang, Xiaowen, Wu, Haiyong, Wang, Qian, Cai, Jian, Cui, Yanmei, Liu, Huanliang, Lan, Ping, Wang, Jianping, Yang, Zihuan, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756236/
https://www.ncbi.nlm.nih.gov/pubmed/31332286
http://dx.doi.org/10.1038/s41388-019-0891-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756236/
https://www.ncbi.nlm.nih.gov/pubmed/31332286
http://dx.doi.org/10.1038/s41388-019-0891-6

Ejemplares similares