Onset of action of naldemedine in the treatment of opioid-induced constipation in patients with chronic noncancer pain: results from 2 randomized, placebo-controlled, phase 3 trials

Opioid-induced constipation (OIC) is a common side effect of chronic opioid therapy. Previously, naldemedine, a peripherally acting μ-opioid receptor antagonist demonstrated efficacy in the treatment of OIC. In this exploratory analysis, the onset of action of naldemedine was evaluated in 2 identica...

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Detalles Bibliográficos
Autores principales: Wild, James, Yamada, Tadaaki, Arjona Ferreira, Juan Camilo, Hale, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756260/
https://www.ncbi.nlm.nih.gov/pubmed/31145214
http://dx.doi.org/10.1097/j.pain.0000000000001629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756260/
https://www.ncbi.nlm.nih.gov/pubmed/31145214
http://dx.doi.org/10.1097/j.pain.0000000000001629

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