Inhibition of esophageal cancer growth through the suppression of PI3K/AKT/mTOR signaling pathway

BACKGROUND: The phosphatidylinositol-3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway is implicated in several cancers. AKT allosteric inhibitor MK2206 and dual PI3K and mTOR inhibitor BEZ235 are promising drug candidates with potential anti-tumor effects.  PURPOSE...

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Detalles Bibliográficos
Autores principales: Shi, Ni, Yu, Hao, Chen, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756275/
https://www.ncbi.nlm.nih.gov/pubmed/31571914
http://dx.doi.org/10.2147/OTT.S205457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756275/
https://www.ncbi.nlm.nih.gov/pubmed/31571914
http://dx.doi.org/10.2147/OTT.S205457

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