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Nerve growth factor antibody for the treatment of osteoarthritis pain and chronic low-back pain: mechanism of action in the context of efficacy and safety

Chronic pain continues to be a significant global burden despite the availability of a variety of nonpharmacologic and pharmacologic treatment options. Thus, there is a need for new analgesics with novel mechanisms of action. In this regard, antibodies directed against nerve growth factor (NGF-Abs)...

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Detalles Bibliográficos
Autores principales: Schmelz, Martin, Mantyh, Patrick, Malfait, Anne-Marie, Farrar, John, Yaksh, Tony, Tive, Leslie, Viktrup, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756297/
https://www.ncbi.nlm.nih.gov/pubmed/31145219
http://dx.doi.org/10.1097/j.pain.0000000000001625