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Nerve growth factor antibody for the treatment of osteoarthritis pain and chronic low-back pain: mechanism of action in the context of efficacy and safety
Chronic pain continues to be a significant global burden despite the availability of a variety of nonpharmacologic and pharmacologic treatment options. Thus, there is a need for new analgesics with novel mechanisms of action. In this regard, antibodies directed against nerve growth factor (NGF-Abs)...
Autores principales: | Schmelz, Martin, Mantyh, Patrick, Malfait, Anne-Marie, Farrar, John, Yaksh, Tony, Tive, Leslie, Viktrup, Lars |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756297/ https://www.ncbi.nlm.nih.gov/pubmed/31145219 http://dx.doi.org/10.1097/j.pain.0000000000001625 |
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