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FLI-06 Intercepts Notch Signaling And Suppresses The Proliferation And Self-renewal Of Tongue Cancer Cells

PURPOSE: The Notch signaling pathway plays an oncogenic role in tongue squamous cell carcinoma. The aim of this study was to inhibit the proliferation and self-renewal of tongue cancer cells by applying Notch signaling pathway inhibitor FLI-06 (Selleck, USA) and to lay a foundation for the clinicall...

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Detalles Bibliográficos
Autores principales: Gan, Rui-huan, Lin, Li-song, Xie, Jing, Huang, Li, Ding, Lin-can, Su, Bo-hua, Peng, Xian-e, Zheng, Da-li, Lu, You-guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756372/
https://www.ncbi.nlm.nih.gov/pubmed/31571917
http://dx.doi.org/10.2147/OTT.S221231