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Computational analysis of naturally occurring resistance-associated substitutions in genes NS3, NS5A, and NS5B among 86 subtypes of hepatitis C virus worldwide

BACKGROUND AND OBJECTIVE: Direct-acting antivirals (DAA) facing resistance continue to be used in some areas worldwide. Thus, identifying hepatitis C virus (HCV) genotypes/subtypes and loci with certain prevalent resistance-associated substitutions (RASs) deserves attention. We investigated the glob...

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Detalles Bibliográficos
Autores principales: Wu, Ruihong, Geng, Dongfeng, Chi, Xiumei, Wang, Xiaomei, Gao, Xiuzhu, Xu, Hongqin, Shi, Ying, Guan, Yazhe, Wang, Yang, Jin, Jinglan, Ding, Yanhua, Niu, Junqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756830/
https://www.ncbi.nlm.nih.gov/pubmed/31571951
http://dx.doi.org/10.2147/IDR.S218584