Cargando…

Cathepsin L secretion by host and neoplastic cells potentiates invasion

The presence of macrophages within breast tumors correlates with metastatic potential. These tumor-associated macrophages often take on a pro-tumorigenic (M2-like) phenotype resulting in the secretion of growth factors and proteases, including the lysosomal protease cathepsin L. Since cathepsin L al...

Descripción completa

Detalles Bibliográficos
Autores principales: Dykes, Samantha S., Fasanya, Henrietta O., Siemann, Dietmar W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756864/
https://www.ncbi.nlm.nih.gov/pubmed/31565189
http://dx.doi.org/10.18632/oncotarget.27182