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Cathepsin L secretion by host and neoplastic cells potentiates invasion
The presence of macrophages within breast tumors correlates with metastatic potential. These tumor-associated macrophages often take on a pro-tumorigenic (M2-like) phenotype resulting in the secretion of growth factors and proteases, including the lysosomal protease cathepsin L. Since cathepsin L al...
Autores principales: | Dykes, Samantha S., Fasanya, Henrietta O., Siemann, Dietmar W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756864/ https://www.ncbi.nlm.nih.gov/pubmed/31565189 http://dx.doi.org/10.18632/oncotarget.27182 |
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