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Mouse mammary tumor virus (MMTV) - like exogenous sequences are associated with sporadic but not hereditary human breast carcinoma

The inheritance of mutated suppressor genes, such as BRCA1 and BRCA2, is acknowledged as an etiological factor in hereditary breast carcinoma (HBC). Two different molecular mechanisms are possible; the Knudson’s “two hits” or the gene haploinsufficiency. Etiology of sporadic breast carcinoma (SBC) i...

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Detalles Bibliográficos
Autores principales: Naccarato, Antonio Giuseppe, Lessi, Francesca, Zavaglia, Katia, Scatena, Cristian, Al Hamad, Mohammad A., Aretini, Paolo, Menicagli, Michele, Roncella, Manuela, Ghilli, Matteo, Caligo, Maria Adelaide, Mazzanti, Chiara Maria, Bevilacqua, Generoso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756874/
https://www.ncbi.nlm.nih.gov/pubmed/31518337
http://dx.doi.org/10.18632/aging.102252