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Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells

The accumulation of autophagosomes and dysfunction at the axonal terminal of neurons play crucial roles in the genesis and development of Alzheimer’s disease (AD). Abnormalities in neuron axonal transport-related proteins prevent autophagosome maturation in AD. Curcumin, a polyphenol plant compound,...

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Detalles Bibliográficos
Autores principales: Liang, Jie, Zhou, Fanlin, Xiong, Xiaomin, Zhang, Xiong, Li, Shijie, Li, Xiaoju, Gao, Minna, Li, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756876/
https://www.ncbi.nlm.nih.gov/pubmed/31488728
http://dx.doi.org/10.18632/aging.102235