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Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells
The accumulation of autophagosomes and dysfunction at the axonal terminal of neurons play crucial roles in the genesis and development of Alzheimer’s disease (AD). Abnormalities in neuron axonal transport-related proteins prevent autophagosome maturation in AD. Curcumin, a polyphenol plant compound,...
Autores principales: | Liang, Jie, Zhou, Fanlin, Xiong, Xiaomin, Zhang, Xiong, Li, Shijie, Li, Xiaoju, Gao, Minna, Li, Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756876/ https://www.ncbi.nlm.nih.gov/pubmed/31488728 http://dx.doi.org/10.18632/aging.102235 |
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