Knockout of p75 neurotrophin receptor attenuates the hyperphosphorylation of Tau in pR5 mouse model

p75 neurotrophin receptor (p75(NTR)) has been implicated in Alzheimer’s disease (AD). However, whether p75(NTR) is involved in Tau hyperphosphorylation, one of the pathologies observed in AD, remains unclear. In our previous study, the extracellular domain of p75(NTR) blocked amyloid beta (Aβ) toxic...

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Detalles Bibliográficos
Autores principales: Mañucat-Tan, Noralyn B., Shen, Lin-Lin, Bobrovskaya, Larisa, Al-hawwas, Mohammed, Zhou, Fiona H., Wang, Yan-Jiang, Zhou, Xin-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756909/
https://www.ncbi.nlm.nih.gov/pubmed/31479419
http://dx.doi.org/10.18632/aging.102202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756909/
https://www.ncbi.nlm.nih.gov/pubmed/31479419
http://dx.doi.org/10.18632/aging.102202

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