Massively parallel RNA device engineering in mammalian cells with RNA-Seq

Synthetic RNA-based genetic devices dynamically control a wide range of gene-regulatory processes across diverse cell types. However, the limited throughput of quantitative assays in mammalian cells has hindered fast iteration and interrogation of sequence space needed to identify new RNA devices. H...

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Detalles Bibliográficos
Autores principales: Xiang, Joy S., Kaplan, Matias, Dykstra, Peter, Hinks, Michaela, McKeague, Maureen, Smolke, Christina D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757056/
https://www.ncbi.nlm.nih.gov/pubmed/31548547
http://dx.doi.org/10.1038/s41467-019-12334-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757056/
https://www.ncbi.nlm.nih.gov/pubmed/31548547
http://dx.doi.org/10.1038/s41467-019-12334-y

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