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Massively parallel RNA device engineering in mammalian cells with RNA-Seq
Synthetic RNA-based genetic devices dynamically control a wide range of gene-regulatory processes across diverse cell types. However, the limited throughput of quantitative assays in mammalian cells has hindered fast iteration and interrogation of sequence space needed to identify new RNA devices. H...
Autores principales: | Xiang, Joy S., Kaplan, Matias, Dykstra, Peter, Hinks, Michaela, McKeague, Maureen, Smolke, Christina D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757056/ https://www.ncbi.nlm.nih.gov/pubmed/31548547 http://dx.doi.org/10.1038/s41467-019-12334-y |
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