Trp–His covalent adduct in bilirubin oxidase is crucial for effective bilirubin binding but has a minor role in electron transfer

Unlike any protein studied so far, the active site of bilirubin oxidase from Myrothecium verrucaria contains a unique type of covalent link between tryptophan and histidine side chains. The role of this post-translational modification in substrate binding and oxidation is not sufficiently understood...

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Detalles Bibliográficos
Autores principales: Kovaľ, Tomáš, Švecová, Leona, Østergaard, Lars H., Skalova, Tereza, Dušková, Jarmila, Hašek, Jindřich, Kolenko, Petr, Fejfarová, Karla, Stránský, Jan, Trundová, Mária, Dohnálek, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757100/
https://www.ncbi.nlm.nih.gov/pubmed/31548583
http://dx.doi.org/10.1038/s41598-019-50105-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757100/
https://www.ncbi.nlm.nih.gov/pubmed/31548583
http://dx.doi.org/10.1038/s41598-019-50105-3

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