The importance of the quaternary structure to represent conformational ensembles of the major Mycobacterium tuberculosis drug target

Flexibility is a feature intimately related to protein function, since conformational changes can be used to describe environmental changes, chemical modifications, protein-protein and protein-ligand interactions. In this study, we have investigated the influence of the quaternary structure of 2-tra...

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Detalles Bibliográficos
Autores principales: Tarabini, Renata Fioravanti, Timmers, Luís Fernando Saraiva Macedo, Sequeiros-Borja, Carlos Eduardo, Norberto de Souza, Osmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757107/
https://www.ncbi.nlm.nih.gov/pubmed/31548581
http://dx.doi.org/10.1038/s41598-019-50213-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757107/
https://www.ncbi.nlm.nih.gov/pubmed/31548581
http://dx.doi.org/10.1038/s41598-019-50213-0

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