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Thrombotic events with recombinant activated factor VII (rFVIIa) in approved indications are rare and associated with older age, cardiovascular disease, and concomitant use of activated prothrombin complex concentrates (aPCC)

PURPOSE: Recombinant activated factor VII (rFVIIa; NovoSeven(®) RT; Novo Nordisk A/S, Bagsvaerd, Denmark) is approved in the United States for the treatment of bleeding and perioperative management in congenital hemophilia with inhibitors (CHwI), acquired hemophilia (AH), congenital factor VII (FVII...

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Detalles Bibliográficos
Autores principales: Rajpurkar, Madhvi, Croteau, Stacy E, Boggio, Lisa, Cooper, David L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757140/
https://www.ncbi.nlm.nih.gov/pubmed/31572039
http://dx.doi.org/10.2147/JBM.S219573