Steady‐state activation and modulation of the synaptic‐type α1β2γ2L GABA(A) receptor by combinations of physiological and clinical ligands

The synaptic α1β2γ2 GABA(A) receptor is activated phasically by presynaptically released GABA. The receptor is considered to be inactive between synaptic events when exposed to ambient GABA because of its low resting affinity to the transmitter. We tested the hypothesis that a combination of physiol...

Descripción completa

Detalles Bibliográficos
Autores principales: Germann, Allison L., Pierce, Spencer R., Senneff, Thomas C., Burbridge, Ariel B., Steinbach, Joe Henry, Akk, Gustav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757177/
https://www.ncbi.nlm.nih.gov/pubmed/31549483
http://dx.doi.org/10.14814/phy2.14230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757177/
https://www.ncbi.nlm.nih.gov/pubmed/31549483
http://dx.doi.org/10.14814/phy2.14230

Ejemplares similares