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Steady‐state activation and modulation of the synaptic‐type α1β2γ2L GABA(A) receptor by combinations of physiological and clinical ligands
The synaptic α1β2γ2 GABA(A) receptor is activated phasically by presynaptically released GABA. The receptor is considered to be inactive between synaptic events when exposed to ambient GABA because of its low resting affinity to the transmitter. We tested the hypothesis that a combination of physiol...
Autores principales: | Germann, Allison L., Pierce, Spencer R., Senneff, Thomas C., Burbridge, Ariel B., Steinbach, Joe Henry, Akk, Gustav |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757177/ https://www.ncbi.nlm.nih.gov/pubmed/31549483 http://dx.doi.org/10.14814/phy2.14230 |
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