Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine

[Image: see text] Nucleoside analogues are widely used in clinical practice as chemotherapy drugs. Arabinose nucleoside derivatives such as fludarabine are effective in the treatment of patients with acute and chronic leukemias and non-Hodgkin’s lymphomas. Although nucleoside analogues are generally...

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Detalles Bibliográficos
Autores principales: Holzer, Sandro, Rzechorzek, Neil J., Short, Isobel R., Jenkyn-Bedford, Michael, Pellegrini, Luca, Kilkenny, Mairi L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757278/
https://www.ncbi.nlm.nih.gov/pubmed/31479243
http://dx.doi.org/10.1021/acschembio.9b00367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757278/
https://www.ncbi.nlm.nih.gov/pubmed/31479243
http://dx.doi.org/10.1021/acschembio.9b00367

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