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Downregulation of XBP1 decreases serous ovarian cancer cell viability and enhances sensitivity to oxidative stress by increasing intracellular ROS levels

Interaction between endoplasmic reticulum (ER) stress and oxidative stress contributes to the occurrence and development of various types of cancer. The X-box-binding protein 1 (XBP1), which is an important transcription factor in ER stress-related pathways, has also been reported to serve a protect...

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Detalles Bibliográficos
Autores principales: Zhang, Gui Hong, Kai, Jin Yan, Chen, Miao Miao, Ma, Qian, Zhong, Ai Ling, Xie, Su Hong, Zheng, Hui, Wang, Yan Chun, Tong, Ying, Tian, Yuan, Lu, Ren Quan, Guo, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757316/
https://www.ncbi.nlm.nih.gov/pubmed/31579421
http://dx.doi.org/10.3892/ol.2019.10772