Pharmacokinetics/pharmacodynamics of chloroquine and artemisinin-based combination therapy with primaquine

BACKGROUND: Activation of hypnozoites of vivax malaria causes multiple clinical relapses, which contribute to the Plasmodium vivax burden and continuing transmission. Artemisinin-based combination therapy (ACT) is effective against blood-stage P. vivax but requires co-administration with primaquine...

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Detalles Bibliográficos
Autores principales: Daher, André, Aljayyoussi, Ghait, Pereira, Dhelio, Lacerda, Marcus V. G., Alexandre, Márcia A. A., Nascimento, Cristiana T., Alves, Júlio Castro, da Fonseca, Laís Bastos, da Silva, Diego Medeiros Dias, Pinto, Douglas Pereira, Rodrigues, Danielle Fonseca, Silvino, Ana Carolina Rios, de Sousa, Taís Nóbrega, de Brito, Cristiana Ferreira Alves, ter Kuile, Feiko O., Lalloo, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757423/
https://www.ncbi.nlm.nih.gov/pubmed/31547827
http://dx.doi.org/10.1186/s12936-019-2950-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757423/
https://www.ncbi.nlm.nih.gov/pubmed/31547827
http://dx.doi.org/10.1186/s12936-019-2950-4

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