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Genome-wide RNAi screen in Drosophila reveals Enok as a novel trithorax group regulator

BACKGROUND: Polycomb group (PcG) and trithorax group (trxG) proteins contribute to the specialization of cell types by maintaining differential gene expression patterns. Initially discovered as positive regulators of HOX genes in forward genetic screens, trxG counteracts PcG-mediated repression of c...

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Detalles Bibliográficos
Autores principales: Umer, Zain, Akhtar, Jawad, Khan, Muhammad Haider Farooq, Shaheen, Najma, Haseeb, Muhammad Abdul, Mazhar, Khalida, Mithani, Aziz, Anwar, Saima, Tariq, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757429/
https://www.ncbi.nlm.nih.gov/pubmed/31547845
http://dx.doi.org/10.1186/s13072-019-0301-x