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iPSC-derived MSC therapy induces immune tolerance and supports long-term graft survival in mouse orthotopic tracheal transplants

BACKGROUND: Lung transplantation is a life-saving surgical replacement of diseased lungs in patients with end-stage respiratory malfunctions. Despite remarkable short-term recovery, long-term lung survival continues to face several major challenges, including chronic rejection and severe toxic side...

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Detalles Bibliográficos
Autores principales: Khan, Mohammad Afzal, Alanazi, Fatimah, Ahmed, Hala Abdalrahman, Shamma, Talal, Kelly, Kilian, Hammad, Mohamed A., Alawad, Abdullah O., Assiri, Abdullah Mohammed, Broering, Dieter Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757436/
https://www.ncbi.nlm.nih.gov/pubmed/31547869
http://dx.doi.org/10.1186/s13287-019-1397-4