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Umbilical cord/placenta-derived mesenchymal stem cells inhibit fibrogenic activation in human intestinal myofibroblasts via inhibition of myocardin-related transcription factor A

BACKGROUND: The lack of anti-fibrotic agents targeting intestinal fibrosis is a large unmet need in inflammatory bowel diseases, including Crohn’s disease and ulcerative colitis. Previous studies have found that perinatal tissue (umbilical cord, UC; placenta, PL)-derived mesenchymal stem cells (MSCs...

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Detalles Bibliográficos
Autores principales: Choi, Yoon Jeong, Koo, Jun Bon, Kim, Hee Yeon, Seo, Jin Won, Lee, Eun Jeong, Kim, Woo Ram, Cho, Joo Young, Hahm, Ki Baik, Hong, Sung Pyo, Kim, Duk Hwan, Yoo, Jun-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757442/
https://www.ncbi.nlm.nih.gov/pubmed/31547873
http://dx.doi.org/10.1186/s13287-019-1385-8