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The simultaneous analysis of mesenchymal stem cells and early osteocytes accumulation in osteoarthritic femoral head sclerotic bone

OBJECTIVE: OA subchondral bone is a key target for therapy development. Osteocytes, the most abundant bone cell, critically regulate bone formation and resorption. Their progenitors, mesenchymal stem cells (MSCs), display altered behaviour in osteoarthritic subchondral bone. This study investigated...

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Detalles Bibliográficos
Autores principales: Ilas, Dragos C, Churchman, Sarah M, Baboolal, Thomas, Giannoudis, Peter V, Aderinto, Joseph, McGonagle, Dennis, Jones, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758575/
https://www.ncbi.nlm.nih.gov/pubmed/31165896
http://dx.doi.org/10.1093/rheumatology/kez130