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Immunogenicity of biologic agents in juvenile idiopathic arthritis: a systematic review and meta-analysis

OBJECTIVE: The clinical impact of anti-drug antibodies (ADAbs) in paediatric patients with JIA remains unknown. This systematic review and meta-analysis aimed to summarize the prevalence of ADAbs in JIA studies; investigate the effect of ADAbs on treatment efficacy and adverse events; and explore th...

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Detalles Bibliográficos
Autores principales: Doeleman, Martijn J H, van Maarseveen, Erik M, Swart, Joost F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758589/
https://www.ncbi.nlm.nih.gov/pubmed/30809664
http://dx.doi.org/10.1093/rheumatology/kez030