Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies

Inhibition of Carbonic Anhydrases (CAs) has been clinically exploited for many decades for a variety of therapeutic applications. Within a research project aimed at developing novel classes of CA inhibitors (CAIs) with a proper selectivity for certain isoforms, a series of derivatives featuring the...

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Detalles Bibliográficos
Autores principales: Milite, Ciro, Amendola, Giorgio, Nocentini, Alessio, Bua, Silvia, Cipriano, Alessandra, Barresi, Elisabetta, Feoli, Alessandra, Novellino, Ettore, Da Settimo, Federico, Supuran, Claudiu T., Castellano, Sabrina, Cosconati, Sandro, Taliani, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758606/
https://www.ncbi.nlm.nih.gov/pubmed/31537132
http://dx.doi.org/10.1080/14756366.2019.1666836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758606/
https://www.ncbi.nlm.nih.gov/pubmed/31537132
http://dx.doi.org/10.1080/14756366.2019.1666836

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