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Fierce Selection and Interference in B-Cell Repertoire Response to Chronic HIV-1

During chronic infection, HIV-1 engages in a rapid coevolutionary arms race with the host’s adaptive immune system. While it is clear that HIV exerts strong selection on the adaptive immune system, the characteristics of the somatic evolution that shape the immune response are still unknown. Traditi...

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Detalles Bibliográficos
Autores principales: Nourmohammad, Armita, Otwinowski, Jakub, Łuksza, Marta, Mora, Thierry, Walczak, Aleksandra M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759071/
https://www.ncbi.nlm.nih.gov/pubmed/31209469
http://dx.doi.org/10.1093/molbev/msz143