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Endoplasmic reticulum stress and proteasome pathway involvement in human podocyte injury with a truncated COL4A3 mutation

BACKGROUND: Collagen type IV (COL4)-related nephropathy includes a variety of kidney diseases that occur with or without extra-renal manifestations caused by COL4A3-5 mutations. Previous studies revealed several novel mutations, including three COL4A3 missense mutations (G619R, G801R, and C1616Y) an...

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Detalles Bibliográficos
Autores principales: Zhang, Hui-Di, Huang, Jian-Ni, Liu, Yun-Zi, Ren, Hong, Xie, Jing-Yuan, Chen, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759124/
https://www.ncbi.nlm.nih.gov/pubmed/31306228
http://dx.doi.org/10.1097/CM9.0000000000000294