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Ex vivo physiological compression of human osteoarthritis cartilage modulates cellular and matrix components
Mechanical stimulation appears to play a key role in cartilage homeostasis maintenance, but it can also contribute to osteoarthritis (OA) pathogenesis. Accumulating evidence suggests that cartilage loading in the physiological range contributes to tissue integrity maintenance, whereas excessive or r...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759151/ https://www.ncbi.nlm.nih.gov/pubmed/31550275 http://dx.doi.org/10.1371/journal.pone.0222947 |