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Ex vivo physiological compression of human osteoarthritis cartilage modulates cellular and matrix components

Mechanical stimulation appears to play a key role in cartilage homeostasis maintenance, but it can also contribute to osteoarthritis (OA) pathogenesis. Accumulating evidence suggests that cartilage loading in the physiological range contributes to tissue integrity maintenance, whereas excessive or r...

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Detalles Bibliográficos
Autores principales: Dolzani, Paolo, Assirelli, Elisa, Pulsatelli, Lia, Meliconi, Riccardo, Mariani, Erminia, Neri, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759151/
https://www.ncbi.nlm.nih.gov/pubmed/31550275
http://dx.doi.org/10.1371/journal.pone.0222947