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From Escherichia coli mutant (13)C labeling data to a core kinetic model: A kinetic model parameterization pipeline
Kinetic models of metabolic networks offer the promise of quantitative phenotype prediction. The mechanistic characterization of enzyme catalyzed reactions allows for tracing the effect of perturbations in metabolite concentrations and reaction fluxes in response to genetic and environmental perturb...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759195/ https://www.ncbi.nlm.nih.gov/pubmed/31504032 http://dx.doi.org/10.1371/journal.pcbi.1007319 |