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From Escherichia coli mutant (13)C labeling data to a core kinetic model: A kinetic model parameterization pipeline

Kinetic models of metabolic networks offer the promise of quantitative phenotype prediction. The mechanistic characterization of enzyme catalyzed reactions allows for tracing the effect of perturbations in metabolite concentrations and reaction fluxes in response to genetic and environmental perturb...

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Detalles Bibliográficos
Autores principales: Foster, Charles J., Gopalakrishnan, Saratram, Antoniewicz, Maciek R., Maranas, Costas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759195/
https://www.ncbi.nlm.nih.gov/pubmed/31504032
http://dx.doi.org/10.1371/journal.pcbi.1007319