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Acquisition of IgG to ICAM-1-Binding DBLβ Domains in the Plasmodium falciparum Erythrocyte Membrane Protein 1 Antigen Family Varies between Groups A, B, and C

Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is an important malaria virulence factor. The protein family can be divided into clinically relevant subfamilies. ICAM-1-binding group A PfEMP1 proteins also bind endothelial protein C receptor and have been associated with cerebral malar...

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Detalles Bibliográficos
Autores principales: Olsen, Rebecca W., Ecklu-Mensah, Gertrude, Bengtsson, Anja, Ofori, Michael F., Kusi, Kwadwo A., Koram, Kwadwo A., Hviid, Lars, Adams, Yvonne, Jensen, Anja T. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759304/
https://www.ncbi.nlm.nih.gov/pubmed/31308082
http://dx.doi.org/10.1128/IAI.00224-19