Chronic dosing with metformin plus bosentan decreases in vitro pulmonary artery contraction from isolated arteries in adults with pulmonary hypertension

Introduction: Pulmonary arterial hypertension (PAH) specific drug therapy using bosentan has significantly improved quality of life and survival, although PAH is still an incurable disease. Recent studies suggest metformin may have additional treatment benefits in PAH. We therefore investigated in v...

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Detalles Bibliográficos
Autores principales: Liao, Shutan, Li, Dongsheng, Hui, Zheng, McLachlan, Craig S, Zhang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759611/
https://www.ncbi.nlm.nih.gov/pubmed/31579458
http://dx.doi.org/10.15171/jcvtr.2019.32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759611/
https://www.ncbi.nlm.nih.gov/pubmed/31579458
http://dx.doi.org/10.15171/jcvtr.2019.32

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