Unraveling Heparan Sulfate Proteoglycan Binding Motif for Cancer Cell Selectivity

Membrane heparan sulfate proteoglycans (HSPG) regulate cell proliferation, migration, and differentiation and are therefore considered key players in cancer cell development processes. Here, we used the NT4 peptide to investigate how the sulfation pattern of HSPG on cells drives binding specificity....

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Detalles Bibliográficos
Autores principales: Brunetti, Jlenia, Riolo, Giulia, Depau, Lorenzo, Mandarini, Elisabetta, Bernini, Andrea, Karousou, Evgenia, Passi, Alberto, Pini, Alessandro, Bracci, Luisa, Falciani, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759624/
https://www.ncbi.nlm.nih.gov/pubmed/31620357
http://dx.doi.org/10.3389/fonc.2019.00843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759624/
https://www.ncbi.nlm.nih.gov/pubmed/31620357
http://dx.doi.org/10.3389/fonc.2019.00843

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