1,3,4-Oxadiazoles by Ugi-Tetrazole and Huisgen Reaction

[Image: see text] Easy to perform, functional group tolerant, and short syntheses of the privileged scaffold oxadiazole are highly desired. Here, a metal-free protocol for MCR-based synthesis of 2,5-disubstituted 1,3,4-oxadiazoles via a Ugi-tetrazole/Huisgen sequence was developed. Optimization and...

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Detalles Bibliográficos
Autores principales: Wang, Qian, Mgimpatsang, Kumchok C., Konstantinidou, Markella, Shishkina, Svitlana V., Dömling, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759755/
https://www.ncbi.nlm.nih.gov/pubmed/31478379
http://dx.doi.org/10.1021/acs.orglett.9b02614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759755/
https://www.ncbi.nlm.nih.gov/pubmed/31478379
http://dx.doi.org/10.1021/acs.orglett.9b02614

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