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Resistance Evolution against Phage Combinations Depends on the Timing and Order of Exposure

Phage therapy is a promising alternative to chemotherapeutic antibiotics for the treatment of bacterial infections. However, despite recent clinical uses of combinations of phages to treat multidrug-resistant infections, a mechanistic understanding of how bacteria evolve resistance against multiple...

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Detalles Bibliográficos
Autores principales: Wright, Rosanna C. T., Friman, Ville-Petri, Smith, Margaret C. M., Brockhurst, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759759/
https://www.ncbi.nlm.nih.gov/pubmed/31551330
http://dx.doi.org/10.1128/mBio.01652-19