Bordetella Adenylate Cyclase Toxin Inhibits Monocyte-to-Macrophage Transition and Dedifferentiates Human Alveolar Macrophages into Monocyte-like Cells

Monocytes arriving at the site of infection differentiate into functional effector macrophages to replenish the resident sentinel cells. Bordetella pertussis, the pertussis agent, secretes an adenylate cyclase toxin-hemolysin (CyaA) that binds myeloid phagocytes through complement receptor 3 (CD11b/...

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Detalles Bibliográficos
Autores principales: Ahmad, Jawid Nazir, Holubova, Jana, Benada, Oldrich, Kofronova, Olga, Stehlik, Ludek, Vasakova, Martina, Sebo, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759761/
https://www.ncbi.nlm.nih.gov/pubmed/31551332
http://dx.doi.org/10.1128/mBio.01743-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759761/
https://www.ncbi.nlm.nih.gov/pubmed/31551332
http://dx.doi.org/10.1128/mBio.01743-19

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