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Montelukast Prevents Mice Against Acetaminophen-Induced Liver Injury

Acetaminophen (APAP) is a widely used over-the-counter antipyretic and analgesic drug. Overdose of APAP is the leading cause of hospital admission for acute liver failure. Montelukast is an antagonist of cysteinyl leukotriene receptor 1 (Cysltr1), which protects from inflammation and oxidative stres...

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Detalles Bibliográficos
Autores principales: Pu, Shiyun, Liu, Qinhui, Li, Yanping, Li, Rui, Wu, Tong, Zhang, Zijing, Huang, Cuiyuan, Yang, Xuping, He, Jinhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759817/
https://www.ncbi.nlm.nih.gov/pubmed/31620001
http://dx.doi.org/10.3389/fphar.2019.01070