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Microbe-Derived Indole Metabolite Demonstrates Potent Multidrug Efflux Pump Inhibition in Staphylococcus aureus

Efflux pumps are always at the forefront of bacterial multidrug resistance and account for the failure of antibiotics. The present study explored the potential of 2-(2-Aminophenyl) indole (RP2), an efflux pump inhibitor (EPI) isolated from the soil bacterium, to overcome the efflux-mediated resistan...

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Detalles Bibliográficos
Autores principales: Tambat, Rushikesh, Jangra, Manoj, Mahey, Nisha, Chandal, Nishtha, Kaur, Manpreet, Chaudhary, Surbhi, Verma, Dipesh Kumar, Thakur, Krishan Gopal, Raje, Manoj, Jachak, Sanjay, Khatri, Neeraj, Nandanwar, Hemraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759831/
https://www.ncbi.nlm.nih.gov/pubmed/31620109
http://dx.doi.org/10.3389/fmicb.2019.02153