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Genome‐Wide Meta‐Analysis of Blood Pressure Response to β(1)‐Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies)

BACKGROUND: There exists a wide interindividual variability in blood pressure (BP) response to β(1)‐blockers. To identify the genetic determinants of this variability, we performed a pharmacogenomic genome‐wide meta‐analysis of genetic variants influencing β(1)‐blocker BP response. METHODS AND RESUL...

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Detalles Bibliográficos
Autores principales: Singh, Sonal, Warren, Helen R., Hiltunen, Timo P., McDonough, Caitrin W., El Rouby, Nihal, Salvi, Erika, Wang, Zhiying, Garofalidou, Tatiana, Fyhrquist, Frej, Kontula, Kimmo K., Glorioso, Valeria, Zaninello, Roberta, Glorioso, Nicola, Pepine, Carl J., Munroe, Patricia B., Turner, Stephan T., Chapman, Arlene B., Boerwinkle, Eric, Johnson, Julie A., Gong, Yan, Cooper‐DeHoff, Rhonda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759913/
https://www.ncbi.nlm.nih.gov/pubmed/31423876
http://dx.doi.org/10.1161/JAHA.119.013115