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Small Heat Shock Proteins, Big Impact on Protein Aggregation in Neurodegenerative Disease

Misfolding, aggregation, and aberrant accumulation of proteins are central components in the progression of neurodegenerative disease. Cellular molecular chaperone systems modulate proteostasis, and, therefore, are primed to influence aberrant protein-induced neurotoxicity and disease progression. M...

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Detalles Bibliográficos
Autores principales: Webster, Jack M., Darling, April L., Uversky, Vladimir N., Blair, Laura J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759932/
https://www.ncbi.nlm.nih.gov/pubmed/31619995
http://dx.doi.org/10.3389/fphar.2019.01047