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Small Heat Shock Proteins, Big Impact on Protein Aggregation in Neurodegenerative Disease
Misfolding, aggregation, and aberrant accumulation of proteins are central components in the progression of neurodegenerative disease. Cellular molecular chaperone systems modulate proteostasis, and, therefore, are primed to influence aberrant protein-induced neurotoxicity and disease progression. M...
Autores principales: | Webster, Jack M., Darling, April L., Uversky, Vladimir N., Blair, Laura J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759932/ https://www.ncbi.nlm.nih.gov/pubmed/31619995 http://dx.doi.org/10.3389/fphar.2019.01047 |
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