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Determination of the DNA repair pathways utilised by acute lymphoblastic leukaemia cells following daunorubicin treatment

OBJECTIVE: DNA double strand breaks (DNA-DSBs) are among the most lethal DNA lesions leading to genomic instability and repaired by either homologous recombination (HR) or the non-homologous end joining (NHEJ) mechanisms. The purpose of this study was to assess the importance and the level of activa...

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Detalles Bibliográficos
Autores principales: Al-Aamri, Hussain Mubarak, Irving, Helen R., Meehan-Andrews, Terri, Bradley, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760046/
https://www.ncbi.nlm.nih.gov/pubmed/31551083
http://dx.doi.org/10.1186/s13104-019-4663-8